HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Irmgard Fischer Selected Research

Plectin

8/2015Plectin isoform P1b and P1d deficiencies differentially affect mitochondrial morphology and function in skeletal muscle.
12/2014Neuromuscular synapse integrity requires linkage of acetylcholine receptors to postsynaptic intermediate filament networks via rapsyn-plectin 1f complexes.
3/2014Chemical chaperone ameliorates pathological protein aggregation in plectin-deficient muscle.
6/2013Linking cytoarchitecture to metabolism: sarcolemma-associated plectin affects glucose uptake by destabilizing microtubule networks in mdx myofibers.
12/2011Targeted proteolysis of plectin isoform 1a accounts for hemidesmosome dysfunction in mice mimicking the dominant skin blistering disease EBS-Ogna.
5/2008Myofiber integrity depends on desmin network targeting to Z-disks and costameres via distinct plectin isoforms.
2/2003Plectin-isoform-specific rescue of hemidesmosomal defects in plectin (-/-) keratinocytes.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown:


Irmgard Fischer Research Topics

Disease

5Muscular Dystrophies (Muscular Dystrophy)
08/2015 - 05/2008
3Epidermolysis Bullosa Simplex (Epidermolysis Bullosa Herpetiformis Dowling Meara)
12/2014 - 02/2003
2Inflammation (Inflammations)
01/2020 - 01/2016
2Neoplasms (Cancer)
06/2018 - 12/2016
2Epidermolysa bullosa simplex and limb girdle muscular dystrophy
08/2015 - 03/2014
1Progeria (Hutchinson Gilford Syndrome)
12/2022
1Hepatocellular Carcinoma (Hepatoma)
12/2016
1Atopic Dermatitis (Atopic Eczema)
01/2016
1Pathological Protein Aggregation
03/2014
1Myofibrillar Myopathy
03/2014
1Congenital Myasthenic Syndromes (Myasthenia Gravis, Congenital)
12/2011
1Inborn Genetic Diseases (Disease, Hereditary)
02/2003

Drug/Important Bio-Agent (IBA)

7PlectinIBA
08/2015 - 02/2003
4Proteins (Proteins, Gene)FDA Link
12/2014 - 05/2008
2DesminIBA
03/2014 - 05/2008
1MicroRNAs (MicroRNA)IBA
12/2022
1thiamine triphosphorate (TTP)IBA
01/2020
1Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2020
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
06/2018
1ChemokinesIBA
01/2016
1Immunoglobulin E (IgE)IBA
01/2016
1CytokinesIBA
01/2016
1Glucose (Dextrose)FDA LinkGeneric
06/2013
1Protein Isoforms (Isoforms)IBA
02/2003

Therapy/Procedure

3Therapeutics
06/2018 - 02/2003